Anti-tumor activity of nanomicelles encapsulating CXCR4 peptide antagonist E5
نویسندگان
چکیده
منابع مشابه
Anti-tumor activity of nanomicelles encapsulating CXCR4 peptide antagonist E5
Cancer is the leading cause of death worldwide, and metastasis is the main attribute to cancer death. CXCR4 and its natural ligand CXCL12 have been known to play a critical role in tumorigenesis, angiogenesis and metastasis. Therefore, designing a new CXCR4 antagonist to prevent tumor metastasis will be of great significance. Herein, a novel chemically synthesized peptide (E5) that has an abili...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2017
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0182697